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NCI Drug Dictionary

  

danazol 
A synthetic androgen derived from ethinyl testosterone. Danazol indirectly reduces estrogen production by decreasing pituitary secretion of follicle-stimulating hormone and luteinizing hormone, and binds to sex hormone receptors in target tissues, thereby exhibiting antiestrogenic, anabolic and weakly androgenic effects. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
US brand names:Danocrine
Winobanin
Foreign brand names:Bonzol
Chronogyn
Cyclomen
Danol
Danoval
Ladogal
Abbreviation:DAN
Code name:Win-17757
Chemical structures:(17alpha)-pregna-2,4-dien-20-yno[2,3-d]-isoxazol-17-ol
17alpha-ethynyl-17beta-hydroxy-4-androsteno[2,3-d]isoxazole
1-ethynyl-2,3,3a,3b,4,5,10,10a,10b,11,12,12a-dodecahydro-10a,12a-dimethyl-1H-cyclopental[7,8]phenanthro[3,2-d]isoxazol-1-ol