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NCI Drug Dictionary

  

therapeutic estradiol 
A steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Typically esterified, estradiol derivatives are formulated for oral or parenteral administration. As the primary, most potent estrogen hormone produced by the ovaries, estradiol binds to and activates specific nuclear receptors. Estradiol exhibits mild anabolic and metabolic properties, and increases blood coagulability. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:17 beta-estradiol
Estraldine
US brand names:Aquadiol
Estrace
Vivelle
Foreign brand names:Dimenformon
Diogyn
Diogynets
Ovocylin
Progynon
Abbreviation:ESDL
Chemical structure:(17beta)-estra-1,3,5(10)-triene-3,17-diol