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NCI Drug Dictionary


allogeneic GM-CSF-secreting breast cancer vaccine 
An allogenic vaccine consisting of irradiated breast cancer cells transfected with the granulocyte macrophage-colony-stimulating factor (GM-CSF) gene. Upon vaccination, the genetically modified cells secrete GM-CSF, thereby potentiating a tumor-specific T cell response against breast cancer cell-asociated antigens. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Abbreviation:GM-CSF BREAST VAC