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NCI Drug Dictionary

  

decitabine  Patient Information
A cytidine antimetabolite analogue with potential antineoplastic activity. Decitabine incorporates into DNA and inhibits DNA methyltransferase, resulting in hypomethylation of DNA and intra-S-phase arrest of DNA replication. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:5-aza-dCyd
deoxyazacytidine
dezocitidine
US brand name:Dacogen
Abbreviations:5AZA
DAC
Chemical structures:2'-deoxy-5-azacytidine
4-amino-1-(2-deoxy-beta-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one
5-aza-2'-deoxycytidine
5-aza-2-deoxycytidine
5-azadeoxycytidine