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NCI Drug Dictionary

NCI Drug Dictionary

  

piperazinedione 
A crystalline antibiotic fermentation product isolated from the bacterium Streptomyces griseoluteus with antineoplastic activity. Piperazinedione alkylates DNA at the N-7 position of guanine, inhibiting DNA replication and inducing cell cycle arrest. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:compound 593A
Merck Compound 593A;
Abbreviation:PZD
Code name:593A