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NCI Drug Dictionary

NCI Drug Dictionary

  

poly ICLC 
A synthetic complex of carboxymethylcellulose, polyinosinic-polycytidylic acid, and poly-L-lysine double-stranded RNA. Poly ICLC may stimulate the release of cytotoxic cytokines and, by inducing interferon-gamma production, may increase the tumoricidal activities of various immunohematopoietic cells. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:poly I:poly C with poly-1-lysine stabilizer
Polyinosinic-Polycytidylic Acid Stabilized with Polylysine and Carboxymethylcellulose
Polyriboinosinic-Polyribocytidylic Acid-Polylysine Carboxymethylcellulose
stabilized polyriboinosinic/polyribocytidylic acid
US brand name:Hiltonol