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NCI Drug Dictionary

  

lidocaine 
A synthetic aminoethylamide with local anesthetic and antiarrhythmic properties. Lidocaine stabilizes the neuronal membrane by binding to and inhibiting voltage-gated sodium channels, thereby inhibiting the ionic fluxes required for the initiation and conduction of impulses and effecting local anesthesia. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
US brand names:Lidothesin
Xylocaine
Xylocitin
Foreign brand names:Cuivasil
Duncaine
Leostesin
Lignocaine
Rucaina
Xylotox
Chemical structures:2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide
2-diethylamino-2',6'-acetoxylidide
omega-diethylamino-2,6-dimethylacetanilide