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NCI Drug Dictionary

  

mesna  Patient Information
A sulfhydryl compound that is used to reduce the incidence of hemorrhagic cystitis associated with certain chemotherapeutic agents. Mesna is converted to a free thiol compound in the kidney, where it binds to and inactivates acrolein and other urotoxic metabolites of ifosfamide and cyclophosphamide, thereby reducing their toxic effects on the urinary tract during urinary excretion. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:mercaptoethane sulfonate
Mesnum
US brand name:Mesnex
Foreign brand names:Ausobronc
Filesna
Mesnil
Mexan
Mistabron
Mistabronco
Mitexan
Mucofluid
Mucolene
Uromitexan
Ziken
Abbreviation:MSA
Code names:D-7093
UCB 3983
Chemical structures:2-mercaptoethanesulfonic acid, sodium salt
sodium 2-mercaptoethane sulfonate