In English | En español
Questions About Cancer? 1-800-4-CANCER

NCI Drug Dictionary

NCI Drug Dictionary

  

medroxyprogesterone 
A synthetic derivative of progesterone administered as an acetate salt (medroxyprogesterone acetate) with antiestrogenic activity. As a do all progestins, medroxyprogesterone binds to and activates nuclear receptors which subsequently bind to and activate target genes for transcription. As an antiestrogen, this agent may inhibit the growth-stimulating effects of estrogen on estrogen-sensitive tumor cells. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonym:medroxyprogesterone acetate
US brand names:Curretab
Depo-Provera
Provera
Provera Dosepak
Abbreviation:MPA
Chemical structures:(6alpha)-17-hydroxy-6-methylpregn-4-ene-3,20-dione
17alpha-hydroxy-6alpha-methylprogesterone
6alpha-methyl-17alpha-hydroxyprogesterone
6alpha-methyl-4-pregnen-17alpha-ol-3,20-dione