In English | En español
Questions About Cancer? 1-800-4-CANCER

NCI Drug Dictionary

NCI Drug Dictionary

  

menogaril 
A semisynthetic derivative of the anthracycline antineoplastic antibiotic nogalamycin. Menogaril intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent is less cardiotoxic than doxorubicin. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
US brand name:Menogarol
Abbreviations:7-OMEN
MEN
TUT-7
Code name:U-52047
Chemical structures:[2R-(2alpha,3beta,4alpha,5beta,6alpha,11alpha,13alpha)]-4-(dimethylamino)-3,4,5,6,11,12,13,14-octahydro-3,5,8,10,13-pentahydroxy-11-methoxy-6,13-dimethyl-2,6-epoxy-2H-naphthaceno[1,2-b]oxocin-9,16-dione
7-(R)-O-methylnogarol
7-con-O-methylnogarol
7-con-O-methylnorgarol