NCI Drug Dictionary
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A synthetic nucleoside analogue of ribofuranosyl with antiviral activity. Ribavirin incorporates into viral nucleic acid, inhibits viral ribonucleic acid (RNA) synthesis, induces viral genome mutations, and inhibits normal viral replication. Ribavirin shows activity against a variety of RNA viruses, especially hepatitis C virus. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
|US brand names:||Rebetol |
|Chemical structures:||1-beta-D-ribofuranosyl-1,2,4-triazolo-3-carboxamide |