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A synthetic, nonsteroidal agent with antiandrogenic properties. Nilutamide preferentially binds to androgen receptors and blocks androgen receptor activation by testosterone and other androgens; this agent may inhibit androgen-dependent growth of normal and neoplastic prostate cells. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
|US brand name:||Nilandron|
|Foreign brand name:||Anandron|
|Chemical structures:||1-(3'-Trifluoromethyl-4'-nitrophenyl)-4,4-dimethylimidazoline-3,5-dione |