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NCI Drug Dictionary

NCI Drug Dictionary

  

perfosfamide 
The active metabolite of the nitrogen mustard cyclophosphamide with potent antineoplastic and immunosuppressive properties. Perfosfamide alkylates DNA, thereby inhibiting DNA replication and RNA and protein synthesis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonym:hydroperoxycyclophosphamide
US brand name:Pergamid
Abbreviation:4-HC
Chemical structures:2-[bis(2-chloroethyl)amino]-4-hydroperoxytetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide
4'-hydroperoxycyclophosphamide
4-hydroperoxycyclophosphamide
4-Pergamid
cis-2-[bis(2-chloroethyl)amino]tetrahydro-3H-1,3,2-oxazaphosphorin-4-yl hydroperoxide P-oxide
cis-4-hydroperoxycyclophosphamide