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NCI Drug Dictionary


GM.CD40L cell vaccine 
A cell-based vaccine composed of irradiated tumor cells transduced with granulocyte-macrophage colony-stimulating factor (GM-CSF) and CD40-ligand (CD40L) genes. Upon administration, this vaccine may stimulate an anti-tumoral dendritic cell-mediated host immune response. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)