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NCI Drug Dictionary

  

Re-186 hydroxyethylidene diphosphonate 
An synthetic compound containing the organic phosphonate hydroxyethylidene diphosphonate (HEDP) labeled with the radioisotope rhenium Re 186. Re-186 hydroxyethylidene diphosphonate binds to hydroxyapatitie in bone, delivering a cytotoxic dose of beta radiation to primary and metastatic bone tumors. Re-186 is a beta emitter with a short half-life, a radioisotope profile that provides localized antitumor radiocytotoxicity while sparing extramedullary bone marrow tissues. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:186Re-etidronate
rhenium Re 186 etidronate
rhenium-186 hydroxyethylidene diphosphonate
Abbreviation:rhenium-186 HEDP