NCI Drug Dictionary
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Re-186 hydroxyethylidene diphosphonate
An synthetic compound containing the organic phosphonate hydroxyethylidene diphosphonate (HEDP) labeled with the radioisotope rhenium Re 186. Re-186 hydroxyethylidene diphosphonate binds to hydroxyapatitie in bone, delivering a cytotoxic dose of beta radiation to primary and metastatic bone tumors. Re-186 is a beta emitter with a short half-life, a radioisotope profile that provides localized antitumor radiocytotoxicity while sparing extramedullary bone marrow tissues. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
rhenium Re 186 etidronate
rhenium-186 hydroxyethylidene diphosphonate