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NCI Drug Dictionary

NCI Drug Dictionary

  

clonidine hydrochloride 
The hydrochloride salt form of clonidine, an imidazoline derivate and centrally-acting alpha-adrenergic agonist as well as antagonist with antihypertensive activity. Clonidine hydrochloride binds to and stimulates central alpha-2 adrenergic receptors, thereby decreasing sympathetic outflow to the heart, kidneys, and peripheral vasculature. The reduction in sympathetic outflow, leads to decreased peripheral vascular resistance, decreased blood pressure, and decreased heart rate. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonym:Catapres-TTS
US brand name:Catapres