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NCI Drug Dictionary

  

methylprednisolone 
A synthetic corticosteroid with anti-inflammatory and immunomodulating properties. Methylprednisolone binds to and activates specific nuclear receptors, resulting in altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cell populations. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:methylprednisolone acetate
methylprednisolone succinate
methylprednisolonum
US brand names:Depo-Medrol
Medlone 21
Medrol
Meprolone
Metrocort
Metypred
Solu-Medrol
Summicort
Foreign brand names:Adlone
A-MethaPred
Asmacortone
Caberdelta M
Cryosolona
DepMedalone
Depo Moderin
Depo-Medrate
Depo-Medrone
Depo-Nisolone
D-Med
Duralone
Emmetipi
Esametone
Firmacort
Medrate
Medrol Veriderm
Medrone
Mega-Star
Metilbetasone Solubile
Metypresol
Metysolon
Prednilem
Predni-M-Tablinen
Radilem
Solpredone
Solu Moderin
Solu-Medrone
Urbason
Veriderm Medrol
Wyacort
Abbreviation:MePRDL
Chemical structures:(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
6alpha-methylprednisolone