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NCI Drug Dictionary

  

daclizumab 
A recombinant monoclonal antibody interleukin-2 receptor antagonist. Daclizumab binds specifically to the alpha subunit of the human interleukin-2 (IL-2) receptor expressed on the surface of activated lymphocytes in vivo, thereby inhibiting IL-2 binding and IL-2-mediated lymphocyte activation, a critical cellular immune response pathway. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:anti-Tac
Anti-Tac Humanized Monoclonal Antibody
anti-Tac monoclonal antibody
Dacliximab
US brand name:Zenapax
Abbreviation:MOAB anti-Tac