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NCI Drug Dictionary

  

satraplatin 
An orally administered third generation platinum compound with potential antineoplastic activity. Satraplatin forms highly reactive, charged, platinum complexes which bind to nucleophilic groups in DNA, inducing intrastrand and interstrand DNA cross-links, as well as DNA-protein cross-links. These cross-links result in cell growth inhibition and apoptosis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
US brand name:Orplatna
Code names:BMS-182751
BMY-45594
JM216
Chemical structures:(OC-6-43)-bis(acetato)amminedichloro(cyclohexylamine)platinum
(OC-6-43)-bis(acetato-O)amminedichloro(cyclohexanamine)platinum
platinum,bis(acetato-O)amminedichloro(cyclohexanamine)-,(OC-6-43)