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NCI Drug Dictionary


disaccharide tripeptide glycerol dipalmitoyl 
A lipophilic disaccharide tripeptide derivative of muramyl dipeptide (MDP) with immunomodulatory activity. Disaccharide tripeptide glycerol dipalmitoyl (DTP-GDP)stimulates macrophage activity and increases serum levels of tumor necrosis factor alpha (TNF alpha), neopterin, interleukin (IL)-1 alpha, IL-1 beta, IL-6, IL-8, and IL-12, which may activate host immune system antitumor functions. DTP-GDP may be packaged in liposomes for improved delivery. The immunomodulatory effects of this agent may be superior to those of MDP. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
US brand name:ImmTher
Chemical structure:N-acetylglucosaminyl-N-acetyhnuramyl-L-Ala-isoGlu-L-Ala-glycerol dipalmitate