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NCI Drug Dictionary

  

epratuzumab 
A recombinant, humanized monoclonal antibody directed against CD22, a cell surface glycoprotein present on mature B-cells and on many types of malignant B-cells. After binding to CD22, epratuzumab's predominant antitumor activity appears to be mediated through antibody-dependent cellular cytotoxicity (ADCC). Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:AMG 412
Humanized Anti-CD22 Monoclonal Antibody IgG1
LL2
monoclonal antibody LL2
US brand name:LymphoCide
Abbreviations:hLL2
MOAB LL2