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NCI Drug Dictionary

NCI Drug Dictionary

  

motexafin gadolinium 
A synthetic metallotexaphyrin with radiosensitizing and chemosensitizing properties. Motexafin gadolinium accumulates in tumor cells preferentially due to their increased rates of metabolism, generating reactive oxygen species (ROS) intracellularly and lowering the tumor cell apoptotic threshold to ionizing radiation and chemotherapy. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:gadolinium texaphyrin
Gd (III) Texaphryin
US brand name:Xcytrin
Abbreviation:Gd-Tex
Code name:PCI-0120