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NCI Drug Dictionary


sargramostim plasmid DNA melanoma vaccine adjuvant 
A vaccine adjuvant consisting of a plasmid DNA encoding sargramostim (a granulocyte macrophage-colony stimulating factor). Upon administration, expressed sargramostim may stimulate a cytotoxic T cell response enhancing the host immune response to a concomitantly administered melanoma vaccine. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonym:GM-CSF plasmid DNA melanoma vaccine adjuvant