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NCI Drug Dictionary

NCI Drug Dictionary

  

eniluracil 
An orally-active fluoropyrimidine analogue. Eniluracil inhibits dihydropyrimidine dehydrogenase, the rate-limiting enzyme that catabolizes and inactivates 5-fluorouracil (5-FU) in the liver. Co-administration of ethynyluracil permits the oral administration of 5-FU. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:5-ethynyluracil
ethynyluracil
Code names:776C85
ADH300004
GW776
GW776C85
Chemical structure:5-ethynyl-2,4(1H,3H)-pyrimidinedione