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NCI Drug Dictionary

  

opioid growth factor 
An endogenous pentapeptide with potential antineoplastic and antiangiogenic activities. Opioid growth factor (OGF) binds to and activates the opioid growth factor receptor (OGFr), present on some tumor cells and vascular cells, thereby inhibiting tumor cell proliferation and angiogenesis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonym:[Met5]-enkephalin
Abbreviation:OGF
Code name:INNO-105