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NCI Drug Dictionary


iodine I 131 chimeric monoclonal antibody G-250 
A radioimmunoconjugate comprised of the chimeric monoclonal antibody G-250 conjugated with iodine I 131 with potential antineoplastic activity. The antibody moiety of iodine I 131 chimeric monoclonal antibody G-250 binds to G-250, a renal-cell carcinoma-associated antigen, delivering cytotoxic iodine I 131 specifically to renal cell carcinoma cells that express G-250. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:I 131 Monoclonal Antibody G-250
iodine I 131 MOAB G-250
iodine I 131 monoclonal antibody G-250
Abbreviation:iodine I 131 MOAB G250