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NCI Drug Dictionary

NCI Drug Dictionary

  

diethylstilbestrol 
DES; the acronym for diethylstilbestrol, a synthetic, nonsteroidal form of estrogen. A well-known teratogen and carcinogen, DES inhibits the hypothalamic-pituitary-gonadal axis, thereby blocking the testicular synthesis of testosterone, lowering plasma testosterone, and inducing a chemical castration. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:diethylstilbestrol dipropionate
diethylstilbestrolum
Sinestrol
stilboestrol dipropionate
US brand names:Acnestrol
Cyren A
Deladumone
Diastyl
Domestrol
Estrobene
Estrosyn
Fonatol
Makarol
Milestrol
Neo-Oestronol I
Oestrogenine
Oestromenin
Oestromon
Palestrol
Stilbestrol
Stilbetin
Stilboestroform
Stilboestrol
Synestrin
Synthoestrin
Vagestrol
Foreign brand names:Antigestil
Apstil
Boestrol
Bufon
Distilbene
Estrogenine
Estromenin
Grafestrol
Microest
Oestromensyl
Serral
Sexocretin
Sibol
Stilboefral
Stilkap
Abbreviation:DES
Chemical structures:(E)-4,4'-(1,2-diethyl-1,2-ethenediyl)bisphenol
3,4-bis(p-hydroxyphenyl)-3-hexene
4,4'-dihydroxy-alpha,beta-diethylstilbene
alpha,alpha'-diethylstilbenediol
trans-bis-(hydroxy-4-phenyl)-3,4 hexene-3