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NCI Drug Dictionary

  

sodium salicylate 
The sodium salt of salicylic acid. As a nonsteroidal anti-inflammatory drug (NSAID), sodium salicylate irreversibly acetylates cyclooxygenases I and II, thereby inhibiting prostaglandin synthesis and associated inflammation and pain. This agent may also activate mitogen-activated protein kinase (p38MAPK), thereby inducing apoptosis in cancer cells. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:salicylate
salicylic acid
salsalate
US brand name:Disalcid
Abbreviation:Na-Sal
Chemical structure:benzoic acid, 2-hydroxy-, monosodium salt