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NCI Drug Dictionary


human papillomavirus 16/18 L1 virus-like particle/AS04 vaccine  Patient Information
A recombinant, bivalent, human papillomavirus (HPV) vaccine, containing virus-like particles for HPV types 16 and 18 linked to the adjuvant ASO4, with potential immunoprotective and antineoplastic properties. Upon administration, HPV 16/18 L1 virus-like particle/ASO4 vaccine may generate humoral and cellular immunity against HPV types-16 and -18 antigens, thereby preventing cervical infection upon exposure to HPV types 16 and 18. In addition, this agent may stimulate an antitumoral cellular immune response against cervical cancer associated with HPV infection. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
US brand name:Cervarix
Foreign brand name:Cervarix
Abbreviation:HPV 16/18 L1 VLP/AS04 VAC
Code name:GSK-580299