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NCI Drug Dictionary


vascular endothelial growth factor antisense oligonucleotide 
An antisense oligonucleotide with potential antiangiogenesis activity. Vascular endothelial growth factor (VEGF) antisense oligonucleotide binds directly to binds VEGF A/C/D mRNA, leading to mRNA degradation and the inhibition of VEGF A-mediated angiogenesis and VEGF C/D-mediated lymphangiogenesis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonym:VEGF antisense oligonucleotide
US brand name:Veglin