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NCI Drug Dictionary

NCI Drug Dictionary

  

vascular endothelial growth factor antisense oligonucleotide 
An antisense oligonucleotide with potential antiangiogenesis activity. Vascular endothelial growth factor (VEGF) antisense oligonucleotide binds directly to binds VEGF A/C/D mRNA, leading to mRNA degradation and the inhibition of VEGF A-mediated angiogenesis and VEGF C/D-mediated lymphangiogenesis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonym:VEGF antisense oligonucleotide
US brand name:Veglin
Abbreviation:VEGF-AS