NCI Drug Dictionary
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A long-acting, amide-type local anesthetic. Bupivicaine reversibly binds to specific sodium ion channels in the neuronal membrane, resulting in a decrease in the voltage-dependent membrane permeability to sodium ions and membrane stabilization; inhibition of depolarization and nerve impulse conduction; and a reversible loss of sensation. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
|US brand names:||Marcaine |
|Foreign brand name:||Marcain|