NCI Drug Dictionary
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A halogenated derivative of 17-alpha-methyltestosterone. Similar to testosterone, fluoxymesterone binds to and activates specific nuclear receptors, resulting in an increase in protein anabolism, a decrease in amino acid catabolism, and retention of nitrogen, potassium, and phosphorus. This agent also may competitively inhibit prolactin receptors and estrogen receptors, thereby inhibiting the growth of hormone-dependent tumor lines. Fluoxymesterone is approximately five times more potent than methyltestosterone. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
|US brand names:||Android-F |
|Foreign brand names:||Oratestin |
|Chemical structures:||(11Beta,17beta)-9-fluoro-11,17-dihydroxy-17-methylandrost-4-en-3-one |