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NCI Drug Dictionary

NCI Drug Dictionary

  

baclofen 
A synthetic chlorophenyl-butanoic acid derivative with muscle relaxant activity. Baclofen acts as a gamma-aminobutyric acid (GABA) agonist specific for GABA-B receptors in the central nervous system (CNS). At spinal and supraspinal sites, this agent reduces excitatory transmission. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
US brand name:Lioresal
Code name:BA34647
Chemical structures:4-Amino-3-(4-chlorophenyl)-butanoic Acid
beta-(Aminomethyl)-4-chlorobenzenepropanoic acid