NCI Drug Dictionary
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A synthetic chlorophenyl-butanoic acid derivative with muscle relaxant activity. Baclofen acts as a gamma-aminobutyric acid (GABA) agonist specific for GABA-B receptors in the central nervous system (CNS). At spinal and supraspinal sites, this agent reduces excitatory transmission. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
|US brand name:||Lioresal|
|Chemical structures:||4-Amino-3-(4-chlorophenyl)-butanoic Acid |