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NCI Drug Dictionary


A fluorinated ether with general anesthetic and muscle relaxant activities. Although the exact mechanism of action has not been established, desflurane, administered by inhalation, appears to act on the lipid matirx of the neuronal membrane, resulting in disruption of neuronal transmission in the brain. This agent may also enhance the synaptic activity of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
US brand name:Suprane
Code name:I 653
Chemical structure:Ethane, 2-(difluoromethoxy)-1,1,1,2-tetrafluoro-,(+-)-