Español
Questions About Cancer? 1-800-4-CANCER
  • Print
  • Facebook
  • Twitter
  • Google+
  • Pinterest

NCI Drug Dictionary

  

indoximod 
A methylated tryptophan with anti-immunosuppressive activity. Indoximod inhibits the enzyme indoleamine 2,3-dioxygenase (IDO), which degrades the essential amino acid tryptophan, and may increase or maintain tryptophan levels important to T cell function. Tryptophan depletion is associated with immunosuppression involving T cell arrest and anergy. Check for active clinical trials or closed clinical trials using this agent.
Synonyms:1-methyl-d-tryptophan
D-(+)-1-methyltryptophan
Abbreviation:1-MT