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NCI Drug Dictionary

NCI Drug Dictionary

  

glioma-associated antigen peptide-pulsed autologous dendritic cell vaccine 
A cancer vaccine comprised of autologous dendritic cells pulsed with synthetic glioma-associated antigen (GAA) peptides with potential antineoplastic activity. Upon administration, this vaccine may stimulate anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against GAA peptide-expressing glioma cells, resulting in tumor cell lysis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Abbreviation:GAA peptide-pulsed autologous dendritic cell vaccine