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NCI Drug Dictionary


MVA-PSA-PAP prostate cancer vaccine 
A cancer vaccine consisting of a recombinant modified vaccinia Ankara (MVA) viral vector encoding genes for prostate specific antigen (PSA) and prostate acid phosphatase (PAP) with potential immunostimulatory and antineoplastic activities. Upon administration, MVA-PSA-PAP prostate cancer vaccine expresses PSA and PAP peptides, which may elicit humoral and cellular immune responses against prostate cancer cells expressing PSA and PAP. Multi-antigen vaccine therapy may be more efficacious than single-antigen therapy vaccine therapy. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:modified vaccinia Ankara (Bavarian Nordic) prostate cancer vaccine