NCI Drug Dictionary
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lidocaine patch 5%
A transdermal patch containing a 5 percent aqueous base solution of the synthetic amide-type anesthetic lidocaine with analgesic activity. Upon topical application and transdermal delivery, the active ingredient lidocaine binds to and blocks voltage-gated sodium channels in the neuronal cell membrane; lidocaine-mediated stabilization of neuronal membranes inhibits the initiation and conduction of nerve impulses and produces a reversible local anesthesia. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
|US brand name:||Lidoderm|