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NCI Drug Dictionary

  

dinaciclib 
A pyrazolo[1,5-a]pyrimidine with potential antineoplastic activity. Dinaciclib selectively inhibits cyclin dependent kinases CDK1, CDK2, CDK5, and CDK9; inhibition of CDK1 and CDK2 may result in cell cycle repression and tumor cell apoptosis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:CDK inhibitor SCH 727965
cyclin-dependent kinase inhibitor SCH 727965
Code name:SCH 727965