NCI Drug Dictionary
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A pyrazolo[1,5-a]pyrimidine with potential antineoplastic activity. Dinaciclib selectively inhibits cyclin dependent kinases CDK1, CDK2, CDK5, and CDK9; inhibition of CDK1 and CDK2 may result in cell cycle repression and tumor cell apoptosis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
|Synonyms:||CDK inhibitor SCH 727965 |
cyclin-dependent kinase inhibitor SCH 727965
|Code name:||SCH 727965|