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NCI Drug Dictionary

NCI Drug Dictionary

  

gp100:154-162 peptide vaccine 
A peptide consisting of amino acid residues 154 through 162 of the melanoma-melanocyte antigen gp100. Vaccination with gp100:154-162 peptide may enhance tumor-specific T-cell immunity. gp100 antigen is a self-antigen expressed by melanocytes, pigmented retinal cells, and most melanoma lesions and is recognized via class I and II HLA-restricted mechanisms. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)