NCI Drug Dictionary
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mammaglobin-A DNA vaccine
A cancer vaccine containing a plasmid encoding the mammaglobin-A gene with potential immunostimulating and antineoplastic activities. Upon administration, mammaglobin-A DNA vaccine may induce both humoral and cytotoxic T lymphocyte (CTL) immune responses against tumor cells that express mammaglobin-A, which may result in decreased tumor growth. The 10 kiloDalton (kD) glycoprotein mammglobin-A is expressed in over 80% of human breast cancers. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
|Abbreviation:||mam-A DNA vaccine|