In English | En español
Questions About Cancer? 1-800-4-CANCER

NCI Drug Dictionary

  

p53 synthetic long peptide (70-251) vaccine 
A peptide vaccine consisting of 10 synthetic long peptides (SLPs), 25-30 amino acids in size and derived from the middle portion of p53 (amino acids 70-251), mixed with the adjuvant Montanide ISA-51 with potential immunostimulatory and antitumor activities. Upon administration, p53 synthetic long peptide (70-251) vaccine may stimulate the host immune system to mount a cytotoxic T-cell lymphocyte (CTL) response against p53-expressing tumor cells. p53, a tumor associated antigen (TAA), may be overexpressed in variety of cancer cell types. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Abbreviation:p53-SLP vaccine