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NCI Drug Dictionary

  

DNP-modified autologous renal cell carcinoma tumor cell vaccine 
A cancer vaccine consisting of autologous renal cell carcinoma (RCC) tumor cells modified with the hapten 2,4-dinitrophenol (DNP) with potential immunostimulating and antineoplastic activities. Administration of DNP-modified autologous renal cell carcinoma tumor cell vaccine may induce a cytotoxic T-lymphocyte (CTL) response against renal cell carcinoma tumor cells. DNP conjugation may enhance the immunogenicity of weakly immunogenic antigens. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonym:dinitrophenyl-modified autologous renal cell carcinoma tumor cell vaccine