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NCI Drug Dictionary

NCI Drug Dictionary

  

natural killer cells ZRx101 
A population of activated, immortalized, interleukin-2 (IL-2)-dependent, cytotoxic natural killer (NK) cells with potential antitumor activity. Natural killer cells ZRx101 are derived from NK-92 cells, having been modified to target tumor-associated antigens (TAAs) upregulated in certain types of cancer. The NK-92 cell line was originally isolated from a patient with large granular lymphocytic (LGL) leukemia/lymphoma. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonym:NK cells ZRx101