NCI Drug Dictionary
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The hydrochloride salt form of oxymorphone, a semisynthetic opioid with a potent analgesic property. Oxymorphone hydrochloride binds to and activates opiate receptors, specifically mu-receptors, in the central nervous system (CNS). This results in sedation, analgesia, decreased gastrointestinal motility, and respiratory depression. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
|US brand names:||Numorphan |
|Chemical structure:||4,5-alpha-epoxy-3,14-dihydroxy-17-methylmorphinan-6-one hydrochloride|