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NCI Drug Dictionary


oxymorphone hydrochloride 
The hydrochloride salt form of oxymorphone, a semisynthetic opioid with a potent analgesic property. Oxymorphone hydrochloride binds to and activates opiate receptors, specifically mu-receptors, in the central nervous system (CNS). This results in sedation, analgesia, decreased gastrointestinal motility, and respiratory depression. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
US brand names:Numorphan
Chemical structure:4,5-alpha-epoxy-3,14-dihydroxy-17-methylmorphinan-6-one hydrochloride