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NCI Drug Dictionary

  

DNA minor groove binding agent PM060184 
A marine-derived, synthetically produced compound with potential antineoplastic activity. DNA minor groove-binding agent PM060184 covalently binds to residues lying in the minor groove of DNA, which may result in delayed progression through S phase, cell cycle arrest in the G2/M phase and cell death. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Code name:PM060184