In English | En español
Questions About Cancer? 1-800-4-CANCER

NCI Drug Dictionary

  

rivaroxaban 
An orally bioavailable oxazolidinone derivative and direct inhibitor of the coagulation factor Xa with anticoagulant activity. Upon oral administration, rivaroxaban selectively binds to both free factor Xa and factor Xa bound in the prothrombinase complex. This interferes with the conversion of prothrombin (factor II) to thrombin and eventually prevents the formation of cross-linked fibrin clots. Rivaroxaban does not affect existing thrombin levels. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
US brand name:Xarelto
Code name:BAY 59-7939
Chemical structure:5-chloro-N-[[2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl]thiophene-2-carboxamide