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NCI Drug Dictionary

  

almurtide 
A synthetic muramyl dipeptide (MDP) H8analogue with potential immunostimulating and antineoplastic activity. As a derivative of the mycobacterial cell wall component MDP, almurtide activates both monocytes and macrophages. This results in the secretion of cytokines and induces the recruitment and activation of other immune cells, which may result in indirect tumoricidal or cytostatic effects. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:n-muramyldipeptide derivative
norMDP
nor-MDP
Code name:Cgp-11637
Chemical structure:N-acetyl-nor-muramyl-L-alanyl-D-isoglutamine