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NCI Drug Dictionary

NCI Drug Dictionary

  

mesalamine 
An agent derived from sulfasalazine, an antiinflammatory agent. Mesalamine may reduce inflammation through inhibition of cyclooxygenase and prostaglandin production. Following rectal or oral administration, only a small amount of mesalamine is absorbed; the remainder, acting topically, reduces bowel inflammation, diarrhea, rectal bleeding and stomach pain. Check for active clinical trials or closed clinical trials using this agent.
Synonym:mesalazine
US brand names:Apriso
Asacol
Lialda
Pentasa
Rowasa
Abbreviation:5-ASA
Chemical structures:5-amino-2-hydroxybenzoic acid
5-aminosalicylic acid