In English | En español
Questions About Cancer? 1-800-4-CANCER

NCI Drug Dictionary

  

ketoprofen 
A propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic effects. Ketoprofen inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis, by prostaglandin synthase, is responsible for the therapeutic effects of ibuprofen. Ketoprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation. Check for active clinical trials or closed clinical trials using this agent.
Synonym:capisten
US brand names:Orudis
Oruvail
Chemical structures:benzeneacetic Acid, 3-benzoyl-alpha-methyl-
propionic scid, 2-(3-benzoylphenyl)-